The concept of microdosing with psilocybin truffles has received a lot of attention in recent years because of its potential benefits for mental health and general well-being. Many people report positive experiences, such as increased creativity, reduced anxiety and depression, and improved mental clarity. However, microdosing is not for everyone, and there are groups of people for whom it is not recommended. Let's take a look at who we wouldn't recommend microdosing with psilocybin truffles.
1. People under 18 years of age
The brain of adolescents is still developing, and it is not fully understood how psilocybin can affect development. Therefore, it is not recommended for persons under 18 years of age to microdose psilocybin truffles.
2. In combination with alcohol or other drugs
Combining psilocybin truffles with alcohol or other drugs can have unpredictable and potentially dangerous effects. This combination can lead to increased anxiety, paranoia and disorientation. It is strongly discouraged to microdose psilocybin truffles while taking other substances.
3. During pregnancy or lactation
There is insufficient research on the effects of psilocybin truffles on pregnant women and their unborn babies. Moreover, psilocybin can pass into breast milk, which can be harmful to a nursing baby. Therefore, microdosing with psilocybin truffles is not recommended during pregnancy or breastfeeding.
4. In combination with certain medicines
Some drugs can interact with psilocybin and cause unwanted side effects. For example, lithium carbonate (lithium) and tramadol are known drugs that are known to interact negatively with psilocybin. If you are on medication, it is advisable to consult with a doctor before you start microdosing.
5. People with a family history of psychosis
There is some evidence that psilocybin can exacerbate or trigger psychosis in people who are already prone to this condition. If you have a family history of psychosis, it is wise to be extra cautious and seek professional advice before microdosing psilocybin truffles.
6. During periods of intense emotional instability, such as grief
Psilocybin truffles can evoke strong emotions and thoughts, and they may not be suitable for people already dealing with intense emotional stress, such as grief or loss. In such cases, it is important to seek professional advice first and take your mental health seriously.
7. Men with colour blindness
There have been reports of visual disturbances in men with colour blindness after using psilocybin truffles. This can be worrying and therefore it is not recommended for men with colour blindness to microdose with psilocybin truffles.
8. People with tinnitus
Some people with tinnitus, a condition characterised by hearing sounds such as ringing or buzzing in the ears, have reported that their symptoms worsened while using psilocybin truffles. This can cause discomfort, which is why microdosing with psilocybin truffles is not recommended for people with tinnitus.
9. We also advise against microdosing in the following cases;
- In combination with antidepressants or monoamine oxidase inhibitors
especially if you are taking antidepressants such as Selective Serotonin Reuptake Inhibitors (SSRIs) or Monoamine Oxidase Inhibitors (MAOIs), or if you are taking or are tapering anxiety medication. This is due to possible interactions and health risks that can occur when combining these medications with microdosing psychedelic substances such as psilocybin from truffles.
- In combination with lithium carbonate
We strongly advise against combining microdosing with lithium carbonate (lithium) because of the potential for serious interactions and health risks. Lithium is often used as a medication to treat mood disorders such as bipolar disorder. It has specific effects on the chemical balance in the brain and central nervous system.
The combination of microdosing psychedelic substances, such as psilocybin from truffles, and lithium can lead to unpredictable and potentially dangerous effects.
- In combination with tramadol
We do not recommend combining microdosing with tramadol as this combination can be potentially dangerous. Tramadol is a powerful opioid painkiller that affects chemical processes in the brain. Psilocybin, the active ingredient in truffles, also affects brain chemistry and can cause psychoactive effects.
The combination of tramadol and psilocybin truffles can lead to unpredictable interactions and serious side effects.
- In case of mental or physical illness and/or disease
It is crucial to remember that the decision to microdose with psilocybin truffles is a personal choice. If you belong to any of the groups mentioned above or if you have any doubts about the suitability of microdosing for you, it is advisable to consult a healthcare professional first. They can guide you in making an informed decision about using psilocybin truffles for your specific situation. Safety and responsibility are always paramount when exploring this interesting, but potentially powerful, therapeutic practice.
Disclaimer
Microdosing truffles is a personal choice and should not be taken lightly. Research has been done on the potential health benefits, it is important to note that microdosing involves the use of potent substances and can lead to adverse side effects if not taken correctly and responsibly. As with any medicine, it is advised to use accordingly and consult a doctor if in doubt.



