{"id":9617,"date":"2023-10-12T10:14:43","date_gmt":"2023-10-12T10:14:43","guid":{"rendered":"https:\/\/wiserootz.nl\/?p=9617"},"modified":"2026-09-03T11:55:28","modified_gmt":"2026-09-03T09:55:28","slug":"microdosing-protocols","status":"publish","type":"post","link":"https:\/\/wiserootz.nl\/en\/microdosing-protocollen\/","title":{"rendered":"Microdosing Protocols: Which Schedule Should You Choose?"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Who is starting with <a href=\"https:\/\/wiserootz.nl\/en\/microdosing-guide\/\">microdosing<\/a> the word soon comes up\u00a0<strong>protocol<\/strong>\u00a0A microdosing protocol is a schedule in which microdosing days alternate with rest days.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">There are various models and approaches. The best known is the&nbsp;<strong>Fadiman protocol<\/strong>, with one microdosing day followed by two rest days.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At Wise Rootz, this is the protocol we recommend.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In this guide, you\u2019ll discover how the Fadiman protocol works, why rest days are a valuable part of the process, and what other microdosing protocols you might come across.<\/p>\n\n\n\n<h2 id=\"h-1-het-fadiman-protocol\" class=\"wp-block-heading\">1. The Fadiman Protocol<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The Fadiman Protocol is named after the psychologist and psychedelic researcher&nbsp;<strong>Dr James Fadiman<\/strong>&nbsp;and is one of the best-known regimens in microdosing.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The principle is simple:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Day 1 \u2014 Microdosing Day<\/strong><br>Take your microdose and see how you feel throughout the day.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Day 2 \u2014 First rest day<\/strong><br>You\u2019re not taking a microdose. Do, however, remain mindful of your experience.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Day 3 \u2014 Second rest day<\/strong><br>You won\u2019t be taking a microdose today either, so you can continue to observe and reflect.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Day 4 \u2014 Another day of microdosing<\/strong><br>The cycle begins again.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">After that, you carry on at the same pace:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>microdose \u2192 rest \u2192 rest \u2192 repeat<\/strong><\/p>\n\n\n\n<h3 id=\"h-waarom-wise-rootz-het-fadiman-protocol-adviseert\" class=\"wp-block-heading\">Why Wise Rootz recommends the Fadiman protocol<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">We think this is a good approach for both beginners and those who already have experience with microdosing.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The two rest days create a gap between the microdosing sessions. This allows you not only to observe how you experience a microdosing day, but also to consciously reflect on the days that follow.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That fits perfectly with our approach to microdosing:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Measure. Observe. Reflect.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For beginners, we also recommend starting with&nbsp;<strong>0.5 grams of fresh microdosing truffles<\/strong>&nbsp;and to observe this amount over several microdosing sessions first.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Does this amount feel right? If so, there\u2019s no reason to automatically increase it any further.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Would you like to find out how to work out your personal amount? Then read our guide on the&nbsp;<strong>the sweet spot for microdosing<\/strong>.<\/p>\n\n\n\n<h2 id=\"h-2-om-de-dag-microdosing\" class=\"wp-block-heading\">2. Every-other-day microdosing<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Another schedule you often come across is microdosing every other day.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The rhythm looks something like this, for example:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Day 1 \u2014 Microdosing Day<\/strong><br><strong>Day 2 \u2014 Rest day<\/strong><br><strong>Day 3 \u2014 Microdosing Day<\/strong><br><strong>Day 4 \u2014 Rest day<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">With this approach, there is one rest day between two microdosing sessions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Some people choose this routine because of its regularity. At Wise Rootz, however, we prefer the&nbsp;<strong>Fadiman protocol with two rest days<\/strong>, as this allows more scope for observing experiences across different moments.<\/p>\n\n\n\n<h2 id=\"h-3-intuitief-microdosen\" class=\"wp-block-heading\">3. Intuitive microdosing<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">With an intuitive approach, no fixed schedule is followed. Each person decides for themselves when a microdosing session is appropriate and how much time should elapse between sessions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The flexibility this offers can be appealing if you already have some experience and have got to know your own reactions well.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For beginners, we actually find that a&nbsp;<strong>fixed structure<\/strong>&nbsp;valuable.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you follow the same protocol over a period of time, it becomes easier to compare microdosing days with rest days and to recognise patterns in your experience.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We therefore recommend that you first gain some experience with the&nbsp;<strong>Fadiman protocol<\/strong>.<\/p>\n\n\n\n<h2 id=\"h-4-het-stamets-protocol\" class=\"wp-block-heading\">4. The Stamets Protocol<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Another well-known regimen within the microdosing community is associated with a mycologist&nbsp;<strong>Paul Stamets<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Within the so-called\u00a0<strong>Stamets Stack<\/strong>\u00a0psilocybin is combined with\u00a0<strong><a href=\"https:\/\/wiserootz.nl\/en\/lions-mane-brain\/\">Lion\u2019s Mane<\/a><\/strong>\u00a0and\u00a0<strong>niacin (vitamin B3)<\/strong>\u00a0and a different dosing schedule is used to that of the Fadiman protocol.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The philosophy behind this approach is therefore broader than just the frequency of microdosing: the combination of different substances also forms part of the protocol.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At Wise Rootz, we deliberately opt for a simpler approach and recommend that&nbsp;<strong>The Fadiman protocol as a basis<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This allows you to focus on your microdosing experience, rest days, your personal dosage and reflection.<\/p>\n\n\n\n<h2 id=\"h-5-microdosing-op-een-ander-moment-van-de-dag\" class=\"wp-block-heading\">5. Microdosing at a different time of day<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">As well as different protocols, you may also come across variations in&nbsp;<strong>the moment when people take their microdose<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Some people, for example, prefer later in the day or in the evening.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We do not regard this as a separate protocol, but rather as part of a specific microdosing schedule.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Wise Rootz recommends that you preferably take your microdose&nbsp;<strong>in the morning<\/strong>&nbsp;to take. Particularly when you\u2019re just starting out, this will give you plenty of time throughout the day to consciously observe how you experience the microdosing session.<\/p>\n\n\n\n<h2 id=\"h-waarom-zijn-rustdagen-belangrijk\" class=\"wp-block-heading\">Why are rest days important?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A microdosing protocol involves more than just the times when you take a microdose.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rest days are part of the process.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That\u2019s precisely when you can compare your experiences.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">How are you feeling today? Does your focus feel any different? How is your mood? And can you spot any differences compared to the previous microdosing day?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By keeping track of these observations over several weeks, you\u2019ll gain a more personalised picture of your experience.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That is also why, at Wise Rootz, we place such great importance on&nbsp;<strong>reflection and tracking<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In the\u00a0<a href=\"https:\/\/wiserootz.nl\/en\/install-wise-rootz-app\/\"><strong>Wise Rootz app<\/strong>\u00a0<\/a>You can record your dosage as well as your observations, intentions and experiences. That way, you don\u2019t have to rely solely on your memory, but can look back at patterns over time.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/wiserootz.nl\/wp-content\/uploads\/2026\/08\/fadiman-protocol-microdosing-schema-wise-rootz-1024x683.png\" alt=\"The Fadiman protocol for microdosing, comprising one microdosing day and two rest days\" class=\"wp-image-13909\" srcset=\"https:\/\/wiserootz.nl\/wp-content\/uploads\/2026\/08\/fadiman-protocol-microdosing-schema-wise-rootz-1024x683.png 1024w, https:\/\/wiserootz.nl\/wp-content\/uploads\/2026\/08\/fadiman-protocol-microdosing-schema-wise-rootz-300x200.png 300w, https:\/\/wiserootz.nl\/wp-content\/uploads\/2026\/08\/fadiman-protocol-microdosing-schema-wise-rootz-768x512.png 768w, https:\/\/wiserootz.nl\/wp-content\/uploads\/2026\/08\/fadiman-protocol-microdosing-schema-wise-rootz-18x12.png 18w, https:\/\/wiserootz.nl\/wp-content\/uploads\/2026\/08\/fadiman-protocol-microdosing-schema-wise-rootz-600x400.png 600w, https:\/\/wiserootz.nl\/wp-content\/uploads\/2026\/08\/fadiman-protocol-microdosing-schema-wise-rootz.png 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2 id=\"h-hoe-lang-volg-je-het-fadiman-protocol\" class=\"wp-block-heading\">How long do you follow the Fadiman protocol?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A microdosing process works best when you consciously set aside a specific period of time for it.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At Wise Rootz, we therefore use the Fadiman protocol as a framework for a&nbsp;<strong>defined microdosing process<\/strong>, with fixed microdosing days, rest days and moments of reflection.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">After a period like that, you can make a conscious effort to take a break and look back:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>What did I experience? What patterns stood out? How did my \u2018sweet spot\u2019 feel? And what did I learn about my own routine?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This way, microdosing remains something you consciously pay attention to.<\/p>\n\n\n\n<h2 id=\"h-welk-microdosingprotocol-adviseren-wij\" class=\"wp-block-heading\">Which microdosing protocol do we recommend?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">For Wise Rootz, it\u2019s clear:<\/p>\n\n\n\n<h3 id=\"h-het-fadiman-protocol\" class=\"wp-block-heading\">The Fadiman Protocol<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Day 1 \u2014 microdose<\/strong><br><strong>Day 2 \u2014 rest day<\/strong><br><strong>Day 3 \u2014 rest<\/strong><br><strong>Day 4 \u2014 microdosing again<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The schedule is simple, allows for breaks between microdoses and is in line with our approach to microdosing:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>measuring, observing and reflecting.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Are you new to microdosing? If so, combine the protocol with a gradual process of determining your personal dose.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><a href=\"https:\/\/wiserootz.nl\/en\/microdosing-instructions\/\">Read our microdosing guide<\/a><\/strong>\u00a0for the full step-by-step guide, or find out how to<a href=\"https:\/\/wiserootz.nl\/en\/microdosing-sweet-spot\/\">\u00a0<strong>the sweet spot for microdosing<\/strong><\/a>\u00a0finds.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Ready to get started in a mindful way? <a href=\"https:\/\/wiserootz.nl\/en\/product-category\/microdosing\/\">Discover the Wise Rootz Microdosing Box.<\/a><\/strong><\/p>\n\n\n\n<h3 id=\"h-disclaimer\" class=\"wp-block-heading\">Disclaimer<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">This information is intended solely for&nbsp;<strong>general and educational purposes<\/strong>&nbsp;and does not constitute medical advice. Scientific research into microdosing and various dosing regimens is still ongoing, and individual experiences may vary.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Microdosing is not suitable for everyone. Do not microdose whilst pregnant or breastfeeding, if you are under 18, or if you have a personal history of psychosis.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Are you taking any medication, do you have a physical or mental health condition, or are you unsure whether microdosing is right for you? If so, please consult a doctor or other qualified healthcare professional beforehand.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"h-\">Always follow the instructions for use provided and do not exceed the recommended maximum amount.<\/p>\n\n\n\n<h2 id=\"h-wetenschappelijke-bronnen\" class=\"wp-block-heading\">Scientific Sources<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"h-\"><strong>Polito V, Stevenson RJ.<\/strong>\u00a0A systematic study of microdosing psychedelics.\u00a0<em>PLOS ONE.<\/em>\u00a02019;14(2):e0211023. doi:10.1371\/journal.pone.0211023.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Fadiman J, Korb S.<\/strong>\u00a0Could Microdosing Psychedelics Be Safe and Beneficial? An Initial Exploration.\u00a0<em>Journal of Psychoactive Drugs.<\/em>\u00a02019;51(2):118\u2013122. doi:10.1080\/02791072.2019.1593561.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Polito V, Liknaitzky P.<\/strong>\u00a0The emerging science of microdosing: A systematic review of research on low-dose psychedelics (1955\u20132021) and recommendations for the field.\u00a0<em>Neuroscience &amp; Biobehavioural Reviews.<\/em>2022;139:104706. doi:10.1016\/j.neubiorev.2022.104706.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Kuypers KPC, Ng L, Erritzoe D, Knudsen GM, Nichols CD, Nichols DE, Pani L, Soula A, Nutt D.<\/strong>Microdosing psychedelics: More questions than answers? An overview and suggestions for future research.\u00a0<em>Journal of Psychopharmacology.<\/em>\u00a02019;33(9):1039\u20131057. doi:10.1177\/0269881119857204.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Fadiman J.<\/strong>\u00a0<em>The Psychedelic Explorer\u2019s Guide: Safe, Therapeutic and Sacred Journeys.<\/em>\u00a0Rochester, Vermont: Park Street Press; 2011.<\/p>","protected":false},"excerpt":{"rendered":"<p>Wie begint met microdosing komt al snel het woord\u00a0protocol\u00a0tegen. Een microdosingprotocol is een schema waarin microdosingdagen en rustdagen elkaar afwisselen. Er bestaan verschillende schema&#8217;s en benaderingen. Het bekendste is het&nbsp;Fadiman-protocol, waarbij \u00e9\u00e9n microdosingdag wordt gevolgd door twee rustdagen. Bij Wise Rootz is dit het protocol dat we adviseren. In deze gids ontdek je hoe het [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10004,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[85],"tags":[],"class_list":["post-9617","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-microdosing"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.8 (Yoast SEO v28.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Microdosing protocol: Fadiman en andere schema&#039;s | Wise Rootz<\/title>\n<meta name=\"description\" content=\"Ontdek 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